中国海洋大学化学化工学院导师：范玉华 正文

　　范玉华 博士，教授，博士生导师。
　　1982.1毕业于山东大学化学系无机化学专业获学士学位，2004.8毕业于中国原子能科学研究院获博士学位。1995年任副教授，1997年破格晋升为教授。
　　
　　研究方向: 配位化学，生物无机化学。主要从事Schiff碱金属配合物的合成、表征、结构测定及应用方面的研究。在国内外学术刊物上发表学术论文近160篇，其中SCI收录近60篇。作为主持人或主要成员完成国家十一五支撑计划项目1项、省级科技计划项目3 项、市级科技计划项目3项。山东省科技厅鉴定项目4项，其中国际先进3项，国内领先1项。稀有金属希夫碱配合物的研究曾获山东省教育厅科技进步三等奖。
　　
　　目前主持国家自然科学基金项目1项，作为主要成员参加国家自然科学基金项目1项：
　　1.新型氨基酸希夫碱铜配合物的合成及在抗肿瘤作用靶点－蛋白酶体中的应用(20971115)，国家自然科学基金, 2010.1－2012.12。
　　2. 以小分子海洋生物活性物质为前躯物配合物的设计合成与抗肿瘤活性研究(21071134)，国家自然科学基金, 2011.1－2013.12。
　　
　　教学方面：现任校级精品课程“无机及分析化学”及“无机及分析化学实验”的课程责任人。先后给本科生、硕士生主讲过9门课程。主持或作为主要成员承担校级本科教研项目6项，发表教学论文多篇。2010年获中国海洋大学“交通银行奖励教师基金”奖二等奖。
　　
　　编写教材：
　　主编《无机及分析化学实验》， 中国海洋大学出版社
　　参编教材三部：山东省高校化学实验新体系立体化系列教材《基础无机化学实验Ⅰ》（化学工业出版社，2003年），《无机化学实验》（海洋大学出版社），《无机化学实验指导》（海洋大学出版社）。

　　近几年发表的代表性论文：
　　1. Qiang Wang, Caifeng Bi, Yuhua Fan, Xia Zhang，Jian Zuo and Sanbin Liu. A novel copper(Ⅱ) complex with Schiff base derived from o-vanillin and L-methionine: Synthesis and crystal structure. Russian Journal of Coordination Chemistry, 2011, 37(3): 228-234. SCI
　　2. Y.H.Fan, Y. F.Wang, C.F. Bi, Q.Wang, X.Zhang. Synthesis, crystal structure, and fluorescence properties of a Two-Dimensional Copper(Ⅱ) complex with Schiff base. Russian Journal of Coordination Chemistry. 2010, 36(7):509-513. SCI
　　3. Xia Zhang, Michael Frezza, Vesna Milacic, LucaRonconi, Yuhua Fan, Caifeng Bi and Q.Ping Dou. Inhibition of Tumor Proteasome Activity by Gold-Dithiocarbamato Complexes via Both Redox-Dependent and-Independent Processes. Journal of Cellular Biochemistry. 2010, 109:162-172. SCI
　　4. Xin-Yu Liu, Yu-Hua Fan, Qiang Wang , Cai-Feng Bi and Yu-Fang Wang. 1-[(Z)- (5- Methyl-2-pyridyl)iminiomethyl]-2-naphtholate.Acta Crystallographica Section E, 2010, 66: o309. SCI
　　5. Jun Yang, Caifeng Bi, Tingting You and Yuhua Fan. Synthesis and crystal structure of 1-(2-(1H-Benzoimidazol-1-yl)ethyl-1H- benzoimidazol-3-ium Chloride Hydrate. Asian Journal of chemistry, 2010, 22(3):1689-1694. SCI
　　6. Xin-Yu Liu, Yu-Hua Fan, Cai-fengBi, QiangWang and Yuan Gao.2-Methoxy-6-[(Z)-[(5-methyl-2-pyridyl) iminomethyl]phenol. Acta Cryst. 2009, E65, o2170. SCI
　　7.Yan Xiao, Caifeng Bi, Yuhua Fan, Shanbin Liu, Xia Zhang, Dongmei Zhang, Yilong Wang and Rong Zhu. Synthesis,characterization and bioactivity of Schiff base copper(Ⅱ) complexes derived from L-glutamine and L-asparagine. Journal of Coordination Chemistry.2009, 62(18):3029-3039. SCI
　　8. S.-Q.Liu, C.-F. Bi, L.-Y.Chen and Y.-H. Fan. 2-[(1,3-Benzothiazol-2-yl) iminomethyl] phenol, Acta Cryst. 2009, E65, o738. SCI
　　9. Qiang Wang, Cai-feng Bi, Da-Qi Wang, Yu-Hua Fan and Ji-Tian Liu.
　　Tetra-μ-acetato-κ8O:O/-bis{[2-(2-furyl)-1-(2-furylmethyl)-1H-benzimidazole-κN3]
　　copper(Ⅱ)}. Acta Cryst. 2009, E65, m867-868. SCI
　　10.QiangWang, Cai-fengBi, Da-Qi Wang and Yu-HuaFan. Dichlorido{N-[1-pyridyl]
　　-ethlidene]ethane-1,2-diamine} copper(Ⅱ). Acta Cryst. 2009, E65, m439 SCI
　　11. Yuhua Fan , Feng Guo, Caifeng Bi, et al. Synthesis, Characterization, and Electrochemical Studies on the Interaction of Binuclear Cu(Ⅱ) Complex with DNA. Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry. 2008, 38(7): 573-576. SCI
　　12. Y. H. Fan , Z. X. Gao, C. F. Bi, et al. Synthesis and Thermal Decomposition Kinetics of La(Ⅲ) Complex with Unsymmetrical Schiff Base Ligand. Journal of Thermal Analysis and Calorimetry. 2008, 91(3):919-923. SCI
　　13. Y. H. Fan , Y. Y. Li, C. F. Bi, et al. Synthesis, Characterization, and Prohibitive Action on Free Radical O2－· of β-Phenylalanine Schiff Base Binuclear Complexes. Russian Journal of Coordination Chemistry. 2008, 34(10):772-774. SCI
　　14. Hui-Jie Ma, Yu-Hua Fan, Qiang Wang, Cai-Feng Bi. Poly[tris(μ3-5-aminoiso
　　-phthalato) diaquadicerium-(Ⅲ)]. Acta Cryst. 2008, E64, m1326. SCI
　　15. Y. H. Fan, X. T. He, C. F. Bi, et al. Synthesis, Characterization and Antibacterial Activity of New Rare-Earth Complexes with Unsymmetrical Schiff Base Ligand. Russian Journal of Coordination Chemistry. 2007, 33(7):546-549. SCI
　　16. Yu-hua Fan, Yan-na Zou, Cai-feng Bi, et al. Synthesis, Crystal Structure and Thermal Decomposition Kinetics of Zn(Ⅱ) Complex with Vanillin. Russian Journal of Coordination Chemistry. 2007, 33(8):582-587. SCI
　　17. Yan Xiao, Cai Feng Bi , Yu Hua Fan，et al. L-glutamine Schiff base copper complex as a proteasome inhibitor and an apoptosis inducer in human cancer cells. International Journal of Oncology. 2008, 33: 1073-1079. SCI
　　18. Xia Zhang, Cai Feng Bi , Yu Hua Fan, et al. Induction of tumor cell apoptosis by taurine Schiff base copper complex is associated the with inhibition of proteasomal activity. International Journal of Molecular Medicine. 2008, 22: 677-682. SCI
　　19. BI, Cai-Feng, ZHANG, Xia, FAN, Yu-Hua, et al. Synthesis and Thermal Decomposition Kinetics of Uranium(Ⅵ) Complex with Unsymmetrical Schiff Base Ligand. Chinese Journal of Chemistry. 2008, 26(2): 265-268. SCI
　　20. A. D. Wang , C. F. Bi , Y. H. Fan, et al. Structure and Coordination Environment of the Zinc Complex with Vanillin of Double-Stranded Helix. Russian Journal of Coordination Chemistry. 2008, 34(7): 475-479. SCI
　　21.Yan Xiao, Cai Feng Bi, Yu Hua Fan, et al. 1,1/,5,5/-Tetramethyl-2,2/-diphenyl-4,4/-[p-phenyl-enebis(methylidymenitrilo)] di
　　-1H-pyrazol-3(2H)-one. Acta Cryst. 2008, E64, o1479. SCI
　　22. Caifeng Bi, Aidong Wang, Yuhua Fan, et al. Synthesis, Crystal Structure and Theoretical Calculation of Ni (Ⅱ) Complex with N,N′-1,2-Cyclohexenylenebis
　　(salicy- lideneimine).Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry. 2007, 37(1): 67-71. SCI
　　23. Bi Caifeng , Ai Xiaokang, Fan Yuhua, et al. Synthesis and Thermal Decomposition Kinetics of La(Ⅲ) Complex with Unsymmetrical Schiff Base. Journal of the Chilean Chemical Society. 2007, 52(4): 1126-1128. SCI
　　24．Li-rong Yang, Cai-feng Bi, Yu-hua Fan, et al. Crystal Structure and Thermodecomposition kinetics of Copper(Ⅱ) Ternary Complex with o-vanillin-taurine Schiff -base and 1,10-Phenanthroline. Asian Journal of Chemistry. 2007, 19(1): 195-204. SCI
　　25．Feng Guo, Cai-Feng Bi, Yu-Hua Fan, et al. Synthesis, Crystal Structure and Antibacterial Properties of N-(2-Hydroxy-1- naphthalidene)-4-aminoantipyrine. Asian Journal of Chemistry. 2007, 19(3): 1846-1852. SCI
　　26. Fan Yuhua, Bi Caifeng, Ai Xiaokang, et al. Synthesis and thermal decomposition kinetics of Er（Ⅲ) complex with unsymmetrical Schiff base ligand. Journal of Coordination Chemistry. 2006, 59(14/20): 1575-1581. SCI
　　27. Fan Yuhua, Bi Caifeng, Liu Siquan, et al. Synthesis and thermal decomposition kinetics of Th (Ⅳ) complex with unsymmetrical Schiff base ligand. Journal of Radioanalytical and Nuclear Chemistry. 2006, 267(1): 89-93. SCI
　　28. FAN Yu-hua BI Cai-feng. Synthesis, Characterization and Thermodecomposition Kinetics of Sm(Ⅲ) Complex with Unsymmetrical Schiff Base Zwitterion Ligand. Chinese Journal of Chemistry. 2006, 24(3): 371-374. SCI
　　29. Zou Yan-Na, Fan Yu-Hua, Bi Cai-feng, et al. Synthesis and Crystal Structure of Zn (Ⅱ) Complex with 2-Aminopyridine and Acetylacetone. Journal of Structural Chemistry. 2006, 25(3): 261-264. SCI
　　30. Xiao-Kang Ai, Cai-Feng Bi, Yu-Hua Fan, et al. 2-[(2-Aminophenylimino)(phen
　　-yl)- methyl]-4-chlorophenol.Acta Crystallographica Section E. 2006, E62,
　　o3475-o3476. SCI
　　31. Li-rong Yang, Cai-feng Bi, Yu-hua Fan, et al. Crystal Structure and Thermodecomposition Kinetics of A Three-Dimensional Supramolecular Mn comlplex with 8-hydroxyquinoline. Russian Journal of Coordination Chemistry. 2006, 32(7): 504. SCI
　　32. Bi Caifeng, Ai Xiaokang, Fan Yuhua, et al. Synthesis, Characterization and Thermal Decomposition Kinetics of Unsymmetrical Schiff Base Complex with Samarium (Ⅲ). Journal of Rare Earths. 2006, 24(Suppl.):7-10. SCI
　　33. Bi Caifeng, Fan Yuhua. et al. Synthesis, Characterization and Antibacterial Activity of New Ln(Ⅲ) Complex with Unsymmetrical Schiff Base Ligand. Journal of Rare Earths. 2005, 23(Suppl.): 536-536. SCI
　　34. Yang Lirong,Bi Caifeng, Fan Yuhua etal. Synthesis, Characterization and Thermodecomposition Kinetics of Terbium(III) Complex with Novel Schiff base Salicylaldehyde-Taurine and 1,10- phenanthroline. Journal of Rare Earths. 2005，23, Suppl. 12: 77-81. SCI
　　35. Bi Caifeng, Fan Yuhua. Synthesis and Characterization of Metal Complexes with Unsymmetrical Tetradentate Schiff Base Ligands. Synth.React.Inorg.Met-Org.Chem. 2004, 34 (4): 687-695. SCI
　　36. Bi Caifeng, Fan Yuhua. Synthesis and Thermodecomposition Kinetics of UO2 (II) Complex With 2-hydroxy-1-naphthadehyde-4aminoantipyrine Journal of Radioanalytical and Nuclear Chemistry. 2004, 262(2): 497-500. SCI

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