石河子大学药学院导师：郑秋生
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石河子大学药学院导师：郑秋生 正文
[导师姓名]郑秋生
[所属院校]
石河子大学
[基本信息]
导师姓名：郑秋生
性别：男
人气指数：2108
所属院校：石河子大学
所属院系：药学院
职称：教授
导师类型：
招生专业：药学、作物学
研究领域：药学；中药学、
[通讯方式]
电子邮件：30843985@qq.com
[个人简述]
郑秋生，1967年10月生，山东寿光人，北京大学博士后，教授。2006年入选教育部新世纪优秀人才。现任滨州医学院中西医结合学院院长，新疆特种植物药资源教育部重点实验室主任，兰州大学兼职教授、中国海洋大学教兼职教授，石河子大学特聘教授。医药领域国家科技重大专项“十二五”计划技术管理专家，国家科技奖励评审专家，国家“863”计划专家库成员，国家学位和研究生教育专家组成员，西北天然药物(中藏药)产业技术创新战略联盟专家技术委员会委员。山东省、河北省、重庆市以及上海市科技奖励和科技计划的评审专家。曾主持或参与国家“863”、“973”、国家自然科学基金等重大研究项目三十余项，先后参与十多个新药开发项目的药效学评价研究工作，其中已申报并批准临床新药9项，待申报或批准临床达10多项，申请相关专利多项。在国内外学术期刊发表论文200余篇，其中SCI、EI收录论文100余篇，出版专著5 部，获得省部级科技进步一等奖2项，二等奖5项。现为多家国际学术期刊编委、约稿人或特邀审稿人。
对口支援西部高校工作十周年突出贡献个人
[科研工作]
1. 异甘草素调控糖代谢诱导黑色素瘤细胞凋亡机制研究，，国家自然科学基金（项目编号31471338）90万元，主持人郑秋生，2015.01-2018.12
2. 甘草查尔酮A 诱导膀胱癌T24 细胞凋亡机制研究，国家自然科学基金（项目编号81260338）55万元，主持人郑秋生，2012-2016；
3. 光果甘草中三种化合物联合分离新技术研发及中试（13C26216516410），科技型中小企业创业投资引导基金，80万元，主持人郑秋生，2014.1-2016.12
4. 新疆独特生境下植物次生多酚类产物的抗肿瘤活性研究，兵团杰出青年基金（项目编号2011CD006）,30万元，主持人郑秋生，2011-2013。
5. 异甘草素诱导HL-60细胞分化机制的研究，国际科技合作计划（2012BC001），13万元，主持人郑秋生，2012-2014；
6. 异甘草素诱导肿瘤细胞从分化到凋亡过程中氧化还原调控机制研究，973计划前期研究专项（2010CB535003），2009-2012主持人，70万元
7. NADPH氧化酶在异甘草素诱导HL-60细胞分化中的作用研究，国家自然科学基金（项目编号30960451），主持人，22万，2010-2012
8. 化药一类抗肿瘤新药维泰醇及维泰醇类化合物成药性研究，科技部重大新药创制科技重大专项（2009ZX09103-141），428.61万元，主持人，2009-2012
9. 活性氧在阿片代谢过程中产生机制及其对阿片受体结合能力的影响 国家自然科学基金（项目编号30860074），主持人，25万元2009-2011
10. 抗肝纤维化复方新药甘草紫参片的研究与开发 国家“十一五”支撑计划 主持人 2007-2009 (2006BAI06A18-22) 180万元
药学；药理学
Current Biochemistry Research编委
SM Journal of Carcinogenesis& Mutagenesis, 编委
Journal of Pharmaceutical Research编委
Journalof Clinical Breast Cancer Research.编委
The Open Bioactive Compound Journal.
Annals of Urological Research, Editorial Board forAnnals of Urological Research,
American Journal of Laboratory Medicine, Editorial Member.
American Journal of Leukemia Research
Journal of Chemistry（ Guest Edit a Special Issue）主编
SRL Urology 编委
Global Journal of Advanced Radiation Research 共同主编
Jacobs Journal of Drug Metabolism and Toxicology （编委）
The Editorial Board of Chinese Journal of Biology 编委
International Journal of Pharmaceutical Sciences and Developmental Research编委
The member of The Society for Free Radical Research会员
世界中医药学会网络药理学专业委员会副会长；
中华预防医学会自由基预防医学专业委员会理事，中国药理学会会员；
山东省心功能研究会健康与养生专业委员会副主任委员；
医药领域国家科技重大专项“十二五”计划技术管理专家，
国家科技奖励评审专家，国家“863”计划专家库成员，
国家学位和研究生教育专家组成员，
西北天然药物(中藏药)产业技术创新战略联盟专家技术委员会委员
新疆特种植物药资源教育部重点实验室主任、学术委员会副主任
1. Dan Wang, Chendong Yang, Zhuien Wang, Yi Yang, Defang Li, Xiaojie Ding, Wenjuan Xu, Qiusheng Zheng. Norcantharidin combined with Coix seed oil synergistically induces apoptosis and inhibits hepatocellular carcinoma growth by downregulating regulatory T cells accumulation. Scientific Reports 7, Article number: 9373 (2017), doi:10.1038/s41598-017-09668-2
2. Dong Wang, Xinjie Zhang, Defang Li, Wenjin Hao, Fanqing Meng, Bo Wang, Jichun Han, and Qiusheng Zheng. Kaempferide Protects against Myocardial Ischemia/Reperfusion Injury through Activation of the PI3K/Akt/GSK-3β Pathway. Mediators of Inflammation,2017, Article ID 5278218
3. Dan Wang, Wenjuan Xu, Xiaoyu Chen, Jichun Han, Lina Yu, Caixia Gao, Wenjin Hao, Xiaona Liu, Qiusheng Zheng and Defang Li. Icariin induces cell differentiation and cell cycle arrest in mouse melanoma B16 cells via Erk1/2-p38-JNK-dependent pathway. Oncotarget, Advance Publications 2017
4. Jichun Han, Dong Wang, Defang Li, Xiaoyu Chen, Bo Wang, Fenghua Wang, Xixona Liu, Jing Shang and Qiusheng Zheng. Licochalcone E protects against carbon tetrachloride‑induced liver toxicity by activating peroxisome proliferator-activated receptor gamma. MOLECULAR MEDICINE REPORTS. July 28, 2017, DOI: 10.3892/mmr.2017.7268
5. Han J, Wang D, Ye L, Li P, Hao W, Chen X, Ma J, Wang B, Shang J, Li D, Zheng Q. Rosmarinic Acid Protects against Inflammation and Cardiomyocyte Apoptosis during Myocardial Ischemia/Reperfusion Injury by Activating Peroxisome Proliferator-Activated Receptor Gamma. Front Pharmacol. 2017 Jul 118:456. doi: 10.3389/fphar.2017.00456. e Collection 2017.
6. Lingling Si, Xinhui Yang, Xinyan Yan, Yanming Wang, Qiusheng Zheng. Isoliquiritigenin induces apoptosis of human bladder cancer T24 cells via the Cyclin-dependent kinases-independent mechanism. Oncology Letters. Published online on:May 12, 2017https://doi.org/10.3892/ol.2017.6159
7. Wang J, Li Y, Yang Y, Chen X, Du J, Zheng Q, Liang Z, Wang Y. A New Strategy for Deleting Animal drugs from Traditional Chinese Medicines based on Modified Yimusake Formula. Sci Rep. 2017 May 47(1):1504. doi: 10.1038/s41598-017-01613-7.
8. Chen XY, Li DF, Han JC, Wang B, Dong ZP, Yu LN, Pan ZH, Qu CJ, Chen Y, Sun SG, Zheng QS. Reprogramming induced by isoliquiritigenin diminishes melanoma cachexia through mTORC2-AKT-GSK3β signaling. Oncotarget. 2017 Mar 29. doi: 10.18632/oncotarget.16655. [Epub ahead of print]
2016
9. Caixia Gao, Xinyan Yan, Bo Wang, Lina Yu, Jichun Han, Defang Li, Qiusheng Zheng: Jolkinolide B induces apoptosis and inhibits tumor growth in mouse melanoma B16F10 cells by altering glycolysis. Scientific Reports 11/2016 2016(6:36114 | DOI: 10.1038/srep36114)., DOI:10.1038/srep36114
10. Lina Yu, Jun Ma, Jichun Han, Bo Wang, Xiaoyu Chen, Caixia Gao, Defang Li, Qiusheng Zheng: Licochalcone B Arrests Cell Cycle Progression and Induces Apoptosis in Human Breast Cancer MCF-7 Cells. Recent Pat Anticancer Drug Discov. 09/2016 11(4)., DOI:10.2174/1574892811666160906091405
11. Shi-Liang Jia, Xue-Ling Wu, Xiao-Xiao Li, Xue-Ling Dai, Zhao-Lan Gao, Zheng Lu, Qiu-Sheng Zheng, Ya-Xuan Sun: Neuroprotective effects of liquiritin on cognitive deficits induced by soluble amyloid-β1-42 oligomers injected into the hippocampus. Journal of Asian natural products research 09/2016 18(12)., DOI:10.1080/10286020.2016.1201811
12. Jichun Han, Defang Li, Xiaoyu Chen, Fanqing Meng, Bo Wang, Xinjie Zhang, Qiusheng Zheng: Effects of Licochalcone A on Cell-cycle Distribution and Glycolysis in Human Bladder Cancer T24 Cells. Journal of food and nutrition research 08/2016 4(8)., DOI:10.12691/jfnr-4-8-9
13. Jichun Han, Defang Li, Xiaoyu Chen, Fanqing Meng, Bo Wang, Xinjie Zhang, Qiusheng Zheng: Hepatoprotective Activities of Huoshan Dendrobium Officinale Kimura et Migo Water Extracts on Carbontetrachloride-induced Hepatotoxicity in Mice.. DOI:10.12691/jfnr-4-8-10
14. Xiaoyu Chen, Ming Yang, Wenjin Hao, Jichun Han, Jun Ma, Caixia Wang, Shiguo Sun, Qiusheng Zheng: Differentiation-inducing and anti-proliferative activities of isoliquiritigenin and all-trans-retinoic acid on B16F0 melanoma cells: Mechanisms profiling by RNA-seq. Gene 07/2016 592(1)., DOI:10.1016/j.gene.2016.07.052
15. Caixia Wang, Wenjuan Xu, Wenjin Hao, Bingsheng Wang, Qiusheng Zheng: Alternol inhibits the proliferation and induces the differentiation of the mouse melanoma B16F0 cell line. Oncology Reports 06/2016 36(2)., DOI:10.3892/or.2016.4844
16. Xinhui Yang, Jiangtao Jiang, Xinyan Yang, Jichun Han, Qiusheng Zheng: Licochalcone A induces T24 bladder cancer cell apoptosis by increasing intracellular calcium levels. Molecular Medicine Reports 05/2016 14(1)., DOI:10.3892/mmr.2016.5334
17. Yanming WANG, Jun MA, Xinyan YAN, Xiaoyu CHEN, Lingling SI, Ying LIU, Jichun HAN, Wenjin HAO, Qiusheng ZHENG: Isoliquiritigenin inhibits proliferation and induces apoptosis via alleviating hypoxia and reducing glycolysis in melanoma B16F10 cells. Recent Patents on Anti-Cancer Drug Discovery 03/2016 11(999)., DOI:10.2174/1573406412666160307151904
18. Wenjuan Wang, Xiaotang Ma, Jichun Han, Mingjie Zhou, Huanhuan Ren, Qunwen Pan, Chunli Zheng, Qiusheng Zheng: Neuroprotective Effect of Scutellarin on Ischemic Cerebral Injury by Down-Regulating the Expression of Angiotensin-Converting Enzyme and AT1 Receptor. PLoS ONE 01/2016 11(1)., DOI:10.1371/journal.pone.0146197
2015
19. Shiliang Jia, Zheng Lu, Zhaolan Gao, Jun An, Xueling Wu, Xiaoxiao Li, Xueling Dai, Qiusheng Zheng, Yaxuan Sun. Chitosan oligosaccharides alleviate cognitive deficits in an amyloid-β1-42-induced rat model of Alzheimer's disease. Int J Biol Macromol. 2016 Feb83:416-25. doi: 10.1016/j.ijbiomac.2015.11.011. Epub 2015 Nov 18.
20. Yun Han, Jun Wu, Tingting Liu, Youdong Hu, Qiusheng Zheng, Binsheng Wang, Haiyan Lin, Xia Li. Separation, characterization and anticancer activities of a sulfated polysaccharide from Undaria pinnatifida. Int J Biol Macromol. 2016 Feb83:42-9. doi: 10.1016/j.ijbiomac.2015.11.049. Epub 2015 Nov 23.
21. Daoxu Qu, Jichun Han, Huanhuan Ren, Wenxiao Yang, Xinjie hang, Qiusheng Zheng, Dong Wang. Cardioprotective Effects of Astragalin against Myocardial Ischemia/Reperfusion Injury in Isolated Rat Heart. Oxidative medicine and cellular longevity, VOLUME 2016 (2016)(ARTICLE ID 8194690,):11 PAGES · DECEMBER 2015
22. Penglong Wang, Xuan Yuan, Yan Wang, Hong Zhao, Xiling Sun, Qiusheng Zheng: Licochalcone C induces apoptosis via B-cell lymphoma 2 family proteins in T24 cells. Molecular Medicine Reports 09/2015 12(5). DOI:10.3892/mmr.2015.4346
23. Xuan Yuan, Hai-tao Niu, Peng-long Wang, Jie Lu, Hong Zhao, Shi-han Liu, Qiu-sheng Zheng, Chang-gui Li: Cardioprotective Effect of Licochalcone D against Myocardial Ischemia/Reperfusion Injury in Langendorff-Perfused Rat Hearts. PLoS ONE 06/2015 10(6):e0128375. DOI:10.1371/journal.pone.0128375
24. Wenjin Hao, Xuan Yuan, Lina Yu, Caixia Gao, Xiling Sun, Dong Wang, Qiusheng Zheng: Licochalcone A-induced human gastric cancer BGC-823 cells apoptosis by regulating ROS-mediated MAPKs and PI3K/AKT signaling pathways. Scientific Reports 05/2015 5:10336. DOI:10.1038/srep10336
25. Mingjie Zhou, Liqun Liu, Wenjuan Wang, Jichun Han, Huanhuan Ren, Qiusheng Zheng, Dong Wang: Role of licochalcone C in cardioprotection against ischemia / reperfusion injury of isolated rat heart via antioxidant, anti-inflammatory, and anti-apoptotic activities. Life sciences 04/2015 132. DOI:10.1016/j.lfs.2015.04.008
26. Mingjie Zhou, Huanhuan Ren, Jichun Han, Wenjuan Wang, Qiusheng Zheng, Dong Wang: Protective Effects of Kaempferol against Myocardial Ischemia/Reperfusion Injury in Isolated Rat Heart via Antioxidant Activity and Inhibition of Glycogen Synthase Kinase-3. Oxidative medicine and cellular longevity 03/2015 Article ID 481405(1):1-8. DOI:10.1155/2015/481405
27. Xuejiao Hou, Jichun Han, Changsheng Yuan, Huanhuan Ren, Ya Zhang, Tao Zhang, Lixia Xu, Qiusheng Zheng, Wen Chen: Cardioprotective Effects of Total Flavonoids Extracted from Xinjiang Sprig Rosa rugosa against Acute Ischemia/Reperfusion-Induced Myocardial Injury in Isolated Rat Heart. Cardiovascular toxicology 01/2015 DOI:10.1007/s12012-015-9308-0
28. Ma jun, Yuan Xuan, Qu Hengyi, Zhang juan, Wang dong, Sun Xiling, Zheng Qiusheng: The role of reactive oxygen species in morphine addiction of SH-SY5Y cells. Life sciences 01/2015 124. DOI:10.1016/j.lfs.2015.01.003
2014
29. Caixia Wang, B Zhang, N Chen, Liangliang Liu, Jinglei Liu, Q Wang, Zhenhua Wang, Xiling Sun, Qiusheng Zheng. Alteronol Induces Differentiation of Melanoma B16F0 Cells. Recent Pat Anticancer Drug Discov. 2014 Sep 23. .201510(1):116-27.
30. Jichun Han, Dong Wang,Bacui Yu, YanmingWang, Huanhuan Ren, Bo Zhang, YonghuaWang, Qiusheng Zheng, Cardioprotection against Ischemia/Reperfusion by Licochalcone B in Isolated Rat Hearts. Oxidative Medicine and Cellular Longevity. Volume 2014, Article ID 134862, 11 pages,http://dx.doi.org/10.1155/2014/134862
31. Zhao H1, Yuan X, Jiang J, Wang P, Sun X, Wang D, Zheng Q. Antimetastatic Effects of Licochalcone B on Human Bladder Carcinoma T24 by Inhibition of Matrix Metalloproteinases-9 and NF-кB Activity. Basic Clin Pharmacol Toxicol. 2014 May 26. doi: 10.1111/bcpt.12273.
32. Binsheng Wang, Du Xing, Dong Wang, Qiusheng Zheng, Jun Ma, Sun Xiling, and Hengyi Qu. Protective effects of Elaeagnus angustifolia leaf extract against Myocardial Ischemia/Reperfusion Injury in Isolated Rat Heart. Journal of Chemistry. Volume 2014, Article ID 693573, 6 pages.
33. Wang Z, Wang D, Liu L, Guo D, Yu B, Zhang B, Han B, Sun XL Zheng QS. Alteronol inhibits the invasion and metastasis of B16F10 and B16F1 melanoma cells in vitro and in vivo. Life Sci. 2014 Mar 798(1):31-8. doi: 10.1016/j.lfs.2013.12.213. Epub 2014 Jan 8，
34. Jiang JT, Yuan X, Wang T, Chen T, Zhao H,Yan XY, Wang ZP, Sun XL, Zheng QS*. Antioxidative and Cardio-protective Effects of Total Flavonoids Extracted from Dracocephalum moldavica L., Cardiovascular Toxicology，2014 Jan 7. 01/2014
35. Yuan X, Li T, Xiao E, Zhao H, Li Y, Fu S, Gan L, Wang Z, Zheng Q*, Wang Z. Licochalcone B inhibits growth of bladder cancer cells by arresting cell cycle progression and inducing apoptosis. Food Chem Toxicol. Food Chem Toxicol. 2014 Mar65:242-51. doi: 10.1016/j.fct.2013.12.030. Epub 2013 Dec 31.
36. Liu L, Zhang B, Yuan X, Wang P, Sun X, Zheng QS*. Alternol induces an S-phase arrest of melanoma B16F0 cells. Cell Biol Int. 2014 Mar38(3):374-80. doi: 10.1002/cbin.10226. Epub 2014 Jan 10.
37. Jiang JT, Yuan X, Zhao H, Yan XY, Sun XL, Zheng QS*. Licochalcone A inhibits proliferation of bladder cancer T24 cells by inducing reactive oxygen species production. Biomed Mater Eng. 201424(1):1019-25. doi: 10.3233/BME-130899.
38. Ya-Xuan Sun, Ting Liu, Xue-Ling Dai, Qiu-Sheng Zheng, Bo-Di，Hui & Zhao-Feng Jiang. Treatment with lutein provides neuroprotection in mice subjected to transient cerebral ischemia. Journal of Asian Natural Products Research, 2014,Vol. 00, No. 0, 1–10,
39. Bo Han, Mingming Zhang, Ting Tang, Qiusheng Zheng，Keyu Wang, Le Li, and Wen Chen. The long–term fate and toxicity of PEG–modified single–walled carbon nanotube isoliquiritigenin delivery vehicles in rats. Journal of Nanomaterials Received 28 October 2013 Journal of Nanomaterials. Volume 2014 (2014), Article ID 257391, 8
40. Yaxuan Sun, Ting Liu，Xueling Dai, Zhaofen Jiang, Zhaolan Gao, Mei Zhang, Dong Wang and Qiusheng Zheng*. Neuroprotective Effect of Dracocephalum moldavica L. Total Flavonoids in Transient Cerebral Ischemia in Rats. Annual Research & Review in Biology. 4(12): 1915-1926，2014
2013年
41. Yuan X, Li DF, Zhao H, Jiang JT, Wang PL, Ma XY, Sun XL, Zheng QS*. Licochalcone-A-Induced Human Bladder Cancer T24 Cells Apoptosis Triggered by Mitochondria Dysfunction and Endoplasmic Reticulum Stress. BioMed Research International. Volume 2013, Article ID 474272, 9 pages
42. Yuan X, Yu BC, Wang YM, Jiang JT, Liu LL, Zhao H, Wang Q, Zheng QS*. Involvement of Endoplasmic Reticulum Stress in Isoliquiritigenin-Induced SKOV-3 Cell Apoptosis. Recent Pat Anticancer Drug Discov. 2013 May 18(2):191-9. PubMed PMID: 22963151.
43. Zhao H, Yuan X, Li DF, Chen HM, Jiang JT, Wang ZP, Sun XL, Zheng QS*. Isoliquiritigen Enhances the Antitumour Activity and Decreases the Genotoxic Effect of Cyclophosphamide. Molecules，2013, 18, 8786-8798 doi:10.3390/molecules18088786
44. Chen HM, Zhang B, Yuan X, Yao Y, Zhao H, Sun XL, Zheng QS*. Isoliquiritigenin-induced effects on Nrf2 mediated antioxidant defence in the HL-60 cell monocytic differentiation. Cell Biol Int. 2013 Jul 24. doi: 10.1002/ cbin.10156.
45. Yuan X, Zhang B, Gan L, Wang ZH, Yu BC, Liu LL, Zheng QS*, Wang ZP. Involvement of the Mitochondrion-dependent and the Endoplasmic Reticulum Stress-signaling Pathways in Isoliquiritigenin-induced Apoptosis of HeLa Cell. Biomed Environ Sci. 2013 Apr26(4):268-76. doi: 10.3967/0895-3988.2013.04.005
46. Yu BC, Wang T, Zhang B, Wang ZH, Zheng QS*. Protective Effects of Total Flavonoids from Dracocephalum moldavica L. on Myocardial Ischemia /Reperfusion Injury in the Isolate Rats Heart. J PURE APPL MICROBIO. April 2013. Vol. 7(Spl. Edn,53-57
47. Han B, Zhang MM, Zheng QS, Wang XC, Tang T, Chen W. Sodium Carboxyl Methyl Cellulose for Improvement of the Determination of Polyethylene Glycol Modified Carbon Nanotubes by Raman Spectroscopy. Analytical Letters, 2013 in on page 130624060632006. Other IDs: 10.1080/00032719.2013.800535
48. Penglong Wang, Fang Ran, Jiangtao Jiang, Bo Zhang, Xiling Sun, Qiusheng Zheng, Skikon induced K562 cell apoptosis through oxidative stress. Medical Plant, 2013,4(10):5-8
2012年
49. Chen XY, Zhang B, Yuan X, Yang F, Liu J, Zhao H, Liu LL, Wang YM, Wang ZH, Zheng QS*. Isoliquiritigenin-induced differentiation in mouse melanoma B16F0 cell line. Oxid Med Cell Longev. 20122012:534934. doi: 10.1155/2012/534934. Epub 2012 Dec 10. PubMed PMID: 23304254 PubMed Central PMCID: PMC3529869. IF=3.93
50. Chen HM, Zhang B, Yao Y, Chen N, Chen XY, Tian H, Wang ZH, Zheng QS*. NADPH oxidase-derived reactive oxygen species are involved in the HL-60 cell monocytic differentiation induced by isoliquiritigenin. Molecules. 2012 Nov 1217(11):13424-38. doi: 10.3390/molecules171113424. PubMed PMID: 23147401, IF=2.428
51. Zhang B, Chen N, Chen HM, Wang ZH, Zheng QS*. The critical role of redox homeostasis in shikonin-induced HL-60 cell differentiation via unique modulation of the Nrf2/ARE pathway. Oxid Med Cell Longev. 20122012:781516. doi:10.1155/2012/781516. Epub 2012 Oct 15. PubMed PMID: 23119122 PubMed Central PMCID: PMC3478756.IF=3.93
52. Li H, Li L, Zheng QS, Kuroda C, Wang Q. Phaeophytin analogues from Ligularia knorringiana. Molecules. 2012 May 717(5):5219-24. doi:10.3390/molecules17055219. PubMed PMID: 22565475. IF=2.428
53. Sun C, Wang ZH, Zheng QS, Zhang H. Salidroside inhibits migration and invasion of human fibrosarcoma HT1080 cells. Phytomedicine. 2012 Feb 1519(3-4):355-63. Epub 2011 Oct 5. IF=3.268
54. Wang D, Yuan X, Liu T, Liu L, Hu Y, Wang Z, Zheng QS*. Neuroprotective activity of lavender oil on transient focal cerebral ischemia in mice. Molecules. 2012 Aug 1517(8):9803-17. doi: 10.3390/molecules17089803. IF=2.428
55. Yuan X, Zhang B, Chen N, Chen XY, Liu LL, Zheng QS*, Wang ZP. Isoliquiritigenin treatment induces apoptosis by increasing intracellular ROS levels in HeLa cells. J Asian Nat Prod Res. 201214(8):789-98. doi: 10.1080/10286020.2012.694873. Epub 2012 Jun 14. IF=0.994
56. Yao Y, Zhang B, Chen H, Chen N, Liu L, Yishan W, Li C, Zheng QS*.Alteronol inhibits proliferation in HeLa cells through inducing a G1-phase arrest. J Pharm Pharmacol. 2012 Jan64(1):101-7. doi: 10.1111/j.2042-7158.2011.01375.x. Epub 2011 Nov 10.
1994.7-1998.7烟台大学化学生物理工学院助教；
1998.7-2002.7烟台大学化学生物理工学院讲师；
2002.7-2004.10 烟台大学化学生物理工学院副教授；2004年破格晋升教授；
2004.9-2005.4 烟台大学海洋学院药物研究所所长；
2003.5-2006.5 烟台绿叶制药有限责任公司新药研发（兼职）；
2006.7-2013.12新疆特种植物药资源教育部重点实验室主任，石河子大学药学院副院长。
2014.01至今 滨州医学院中西医结合学院院长。
[教育背景]
1987.9-1991.6 兰州大学生物系动物学专业学习，同年推荐免试硕士研究生；
1991.9.-1994.6 兰州大学生物物理专业学习，获理学硕士学位；
2000.9-2003.6 兰州大学细胞生物学专业学习，获理学博士学位；
2005.5-2008.9 北京大学天然药物与仿生药物国家重点实验室博士后流动站工作。 以上老师的信息来源于学校网站，如有更新或错误，请联系我们进行更新或删除，联系方式
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